18271560 Item Items
Warning: Last items in stock!
Psychedelics are a class of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips"). This causes specific psychological, visual, and auditory changes, and often a substantially altered state of consciousness. The "classical" psychedelics, the psychedelics with the largest scientific and cultural influence, are mescaline, LSD, psilocybin, and DMT. 4-MeO-DMT.
Most psychedelic drugs fall into one of the three families of chemical compounds: tryptamines, phenethylamines, or lysergamides and many tend to act via serotonin 2A receptor agonism.
Tryptamine is an indolamine metabolite of the essential amino acid tryptophan. The chemical structure is defined by indole-fused benzene and pyrrole ring, and a 2-aminoethyl group at the third carbon.
The structure of tryptamine is a shared feature of certain aminergic neuromodulators, including melatonin, serotonin, bufotenin, and psychedelic derivatives such as dimethyltryptamine (DMT), psilocybin, psilocin, and others. Tryptamine has been shown to activate trace amine-associated receptors expressed in the mammalian brain and regulate the activity of dopaminergic, serotonergic, and glutamatergic systems. In the human gut, symbiotic bacteria convert dietary tryptophan to tryptamine, which activates 5-HT4 receptors and regulates gastrointestinal motility. Multiple tryptamine-derived drugs have been developed to treat migraines, while trace amine-associated receptors are explored as a potential treatment target for neuropsychiatric disorders.
O-Acetylpsilocin (also known as psilacetin, 4-acetoxy-DMT, 4-AcO-DMT, or synthetic shrooms) is a semi-synthetic psychoactive drug that has been suggested be a potentially useful alternative to psilocybin for pharmacological studies, as they are both believed to be prodrugs of psilocin. However, some users report that O-acetylpsilocin's subjective effects differ from those of psilocybin and psilocin. Some users prefer it over natural psilocybin mushrooms due to more minor adverse side effects such as nausea and heavy body load, which the raw mushroom sometimes produces.
O-Acetylpsilocin can be gotten by acetylation of psilocin under alkaline or strongly acidic conditions.
It is, in this manner, a semi-synthetic compound. It is accepted to be a prodrug of psilocin; in any case, a hypothesis exists that psilacetin itself likewise might be psychoactive.
O-Acetylpsilocin is safer than psilocin to oxidation under essential conditions because of its acetoxy bunch.
While O-acetylpsilocin isn’t well-informed (some of the time seen adversely as a research synthetic, instead of psilocin and psilocybin), it isn’t pretty much as troublesome as psilocybin to blend. 4 meo dmt.